Fried Chicken & Biscuit Sandwich

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Imagine this: Mouthwatering chicken coated with golden corn flake breading, snuggled between moist and flakey buttermilk biscuits. 

Here’s the good news: You can eat exactly just that today – and every day!

What’s more is you don’t have to feel guilty about it, plus it comes with more protein! So get your skillet and air fryer ready! We’re going to teach you how to make a High Protein Fried Chicken and Biscuit Sandwich you can enjoy at just over 330 calories! 

Fried chicken and biscuit sandwich with mayo, shredded lettuce, pickles, and hot honey sauce.

There are just those times when you crave something so bad you think about it for days. Well, that happened with us last week. The one we’re drooling over? McDonald’s Biscuits. Think of those chewy, fluffy biscuits that are perfect with gravy – we really can’t blame anyone for wanting those. But unfortunately, they are also high in sodium, fat, and calories.

Well, worry not! You can still taste those scrumptious biscuits at only 138 calories. Throw in some chicken, pickles, and honey, and you’ve got yourself a sandwich that’s to die for!

How To Make Fried Chicken & Biscuit Sandwiches

For the lowest calorie option, you’ll want to make the biscuit recipe listed here. For the quickest option you can use any store bought or ready-to-bake biscuits. You’ll still have a healthier sandwich on your hands and with the chicken, there will definitely be ample protein.

Follow the recipe below and check out the video if you want to see all the steps in action. For more in-depth information on ingredients, substitutions, variations, expert tips, and more, reference the full post after the recipe card.

Important Notice About Measurements

While every effort has been made to make sure the US / volumetric measurements are generally accurate, We do not recommend using them for the biscuit portion of this recipe. There is no guarantee your specific ingredients or your specific scooping technique will measure the same as ours. For the best results, especially with baking recipes such as this one, use a food scale and measure by weight.

The chicken and sauce portions of this recipe have more leeway, so feel free to use volumetric measurements if that’s your preference.

Fried chicken and biscuit sandwich with mayo, shredded lettuce, pickles, and hot honey sauce.

Fried Chicken & Biscuit Sandwiches

This high protein fried chicken & biscuit sandwich tastes like you're eating something you shouldn't. So delicious and so packed with protein.
Prep Time 30 minutes
Cook Time 20 minutes
Course Main Course
Cuisine American
Servings 8 sandwiches
Calories 338 kcal


  • Cast iron skillet
  • Air fryer
  • Hand mixer
  • Mesh strainer
  • Biscuit cutter


  • 900 g chicken breast

Protein Biscuits – Dry Ingredients

  • 150 g all-purpose flour
  • 50 g unflavored whey protein unflavored
  • 50 g casein protein unflavored
  • 20 g collagen peptides
  • 15 g baking powder
  • 6 g salt
  • 1.3g g baking soda

Protein Biscuits – Wet Ingredients

  • 100 g light sour cream
  • 100 g fat-free Greek yogurt
  • 50 g egg
  • 2.5g g butter flavor optional

Chicken Marinade

  • 250 g fat-free milk
  • 15 g white vinegar
  • g hot sauce
  • g garlic powder
  • g salt
  • g black pepper


  • 60 g corn flakes cereal
  • 30 g all-purpose flour
  • 30 g collagen peptides
  • g salt
  • g black pepper

Hot Honey Sauce

  • 15 g honey
  • 30 g sugar-free honey
  • g hot sauce


  • shredded lettuce
  • pickles
  • light mayonnaise


  • Preheat your oven to 425F/220C

Marinate the Chicken

  • Flatten the chicken breasts and cut into 8 pieces about 3-4 inches wide
  • Add all chicken marinade ingredients to a container or bag and mix. Add the chicken, shake to coat completely, and refrigerate for at least 30 minutes.

Prepare the Biscuit Dough

  • Add all biscuits wet ingredients to a bowl and mix with hand mixer
  • Sift in whey, casein, and collagen, then mix on high with hand mixer until light and fluffy
  • Set aside 20-25g of flour for later, then sift in remaining biscuit dry ingredients and mix gently until combined. Cover and refrigerate for ~30 minutes.

Shape, Cut, and Bake the Biscuits

  • Place a piece of parchment on your surface and dust it with flour. Empty biscuit dough onto the paper, then dust it with flour.
  • Flatten the dough and fold it into thirds like folding a letter. Flip it over and dust with more flour. Repeat this step 3 more times, adding flour to the paper and dough as needed to prevent sticking. (You can and should use all of the four that was set aside)
  • Using your biscuit cutter as a guide, flatten the dough so it will fit 2 rows of 3 biscuits (for a total of 6).
  • To cut each biscuit, place the cutter on the dough and press straight down, then pull straight out. Do not twist because that will seal off the layers. Between each cut, it is helpful to wipe any dough off the cutter to prevent sticking.
  • Gather the scraps and shape to fit 2 more biscuits. Gather the final scraps and if there is enough, make one more biscuit (this last one might be thinner).
  • Spray a cast iron skillet with oil, then place into it, making sure they are all touching each other (this helps them rise vertically rather than in all directions).
  • Bake at 425F/220C for 5 minutes, then reduce temperature to 325F/165C and bake for another 10 minutes. Remove from the oven and the pan immediately, placing them on a wire cooling rack.

Bread Air Fry the Chicken

  • In a large dish, crush the corn flakes, then add the remaining breading ingredients
  • Take each piece of chicken out of the marinade (letting excess liquid drop off), coat in the breading, and set on a plate. Repeat for all piece of chicken. If you have breading left over, you can keep pressing the chicken pieces into it until most is used up.
  • Spray lightly with some oil and air fry at 390F/200C for 10-15 minutes or until breading is golden brown and crispy and the chicken has reached an internal temp of 165F/75C

Make Hot Honey Sauce

  • In a small bowl, mix together honey, sugar free honey, and hot sauce.

Build Sandwiches

  • Split a biscuit in the center, add light mayo, shredded lettuce, and a piece of chicken. Drizzle with honey sauce, add a few pickles, put on the biscuit top and… enjoy



  • Feel free to use any biscuits to make the recipe simpler. Using this protein biscuit recipe just really boosts the macros (protein up, carbs down, fat down) but isn’t necessary depending on your specific calorie and macro goals.
Keyword Biscuits, Chicken, Honey

Why You’ll Love This Fried Chicken Biscuit Sandwich Recipe

Lower Calorie, Higher Protein Biscuit

This sandwich recipe isn’t much different from one using regular buttermilk biscuits. You can use whatever biscuit recipe you want in its place, even store bought or ready-to-bake biscuits, but we highly recommend you try our buttermilk biscuit at least once. (We only need one time to convince you to love our lower calorie biscuits!)

Crispy Chicken with Corn Flake Breading

The corn flake breading makes this chicken so deliciously crispy that you won’t believe it’s not deep fried. The special breading mixture with corn flakes, when air fried, makes for a wonderful combination with the biscuit and toppings.

Fits All Diets

This overall high-protein meal works with any diet you’re following. Unlike traditional fried chicken and biscuit sandwiches, you can limit your carbs and fats without getting jealous of anyone munching on regular fried chicken biscuit sandwiches.

Oozing with Flavors

The blend of lower-sugar hot honey sauce, pickles, and light mayonnaise rounds out the flavors and makes the sandwich feel extra indulgent. Lower calorie restrictions don’t mean you have to settle for fewer to no flavors!

Protein Buttermilk Biscuit Ingredients

All-Purpose Flour

Let’s keep that traditional biscuit flavor and texture. An all-purpose flour mixture is typical for baking but is also a source of calcium and iron.

Unflavored Whey and Casein Protein

Using a whey casein blend for protein baking usually provides better results than just one or the other, as they’re an excellent mix for protein synthesis and muscle growth. The whey adds more fluffiness, while the casein holds more moisture. Both are unflavored, so we can control how the biscuits taste and make them taste exactly like your favorite buttermilk biscuits.

Collagen Peptides

Collagen peptides don’t gel when mixed with liquids, so you can easily use them without fretting over changing the food texture. It even adds more protein and tenderness to protein baked goods. You’ll also enjoy collagen’s benefits like improved skin, hair, and joints, easier digestion, and better heart health.

Baking Powder

We prefer baking powder for the biscuit dough to keep true to the original biscuit recipe. You don’t have to mess around with yeast, especially if you’re a newbie baker. Yeast can be time-consuming and, if not prepared correctly, can lead to wasted ingredients. We also add a little baking soda for flavor.

Light Sour Cream and Fat-Free Greek Yogurt

We use a combo of these ingredients to add the acidity which brings out that buttermilk flavor. When developing this recipe, we tried using real buttermilk and even a milk and vinegar mixture but found the best results simply with the acidity from the sour cream and yogurt.

As a bonus, sour cream aids the absorption of fat-soluble vitamins (Vitamins A, D, E, and K). Aside from adding more protein, Greek yogurt reduces hunger and boosts metabolism.


The egg yolk is our only source of fat for the biscuit recipe and is necessary for tenderness and maintaining moisture. The fat content also offers an extra-rich flavor and texture. Yolks contain vitamins and choline that the brain and nervous system need to function.

Butter Flavor

Adding butter flavor is completely optional, but in testing this recipe, we liked the results better when it was added. We also tested versions with real butter and found the benefit to the taste was negligible and not worth the added calories. If you want to make the biscuits higher in calories and maybe slightly more flavorful and tender, you can absolutely use real butter in this recipe.

Corn Flake Fried Chicken Ingredients


We use a combination of fat-free milk and vinegar as a substitute for buttermilk. Then we add in some hot sauce and spices for flavor.

Corn flakes

Corn flakes are perfect for a really special crunch that tastes and feels extremely indulgent. They are also easier to prepare compared to others.

There are many different types of breading you can use with chicken, and they would all work with this sandwich, but the cornflakes make it feel extra Southern and pair so well with the buttermilk biscuit and hot honey sauce.

All-purpose flour

As is typical with our recipes, we include some regular flour for traditional flavor and texture. All-purpose flour has a moderate protein content of 10% to 12%.

Collagen peptides

When used as a breading, collagen melts and becomes crunchy and chewy. Aside from the benefits we already discussed above, collagen peptides are great compared to other protein powders that dry out when used in such a low moisture situation.


Hot honey sauce

It’s just a simple mixture of honey and our favorite hot sauce, except we replace most of the regular honey with sugar-free honey. If you have room for the calories and sugar in your diet, you can use real honey. Or, if you want to save even more calories, opt for just the sugar-free honey. Either will work fine, but we found the best taste with a combination of the two.

Shredded lettuce

Lettuce is great if you’re calorie counting since it’s extremely low in calories. When eaten fresh, lettuce gives a nice crispness, crunch, and fiber.


These go great on any chicken sandwich. We prefer sliced dill pickles, but you can use any pickles you like or leave them out entirely. Pickles also help digestion as they are full of probiotics necessary for gut health.

Light mayonnaise

We personally can’t taste much of a difference between light mayo and regular mayo, so this is always our go-to option. Light mayo saves a bunch of calories and still gives plenty of traditional flavors. It also keeps the sandwich from feeling dry and gives a creamy taste.


Store Bought Biscuits

If you have no time to make your own biscuits, you can buy them at the store. You just have to watch out for their calorie content.

Nuts for Chicken Coating

You can use a variety of crushed nuts, like macadamia, pistachios, almonds, peanuts, pecans, or a combination. Nuts offer different textures and flavors. This customization also lets you meet nutrition-serving requirements like fibers and healthy fats. This is an option for reducing carbs but the tradeoff is increased fat and calories.


You’re free to use whatever sauce you prefer, whether it be Chipotle Mayo, teriyaki sauce, BBQ sauce or others. It all depends on your preference and calorie limits.

Spicy Fried Chicken

If you want some kick to your chicken biscuit sandwiches, then you can go for some spicy fried chicken. To make this, simply coat the chicken with more hot sauce after air frying.

Chicken Thigh

Chicken breasts are the healthiest cut, but you can also use boneless skinless chicken thighs. Boneless skinless chicken thighs are excellent substitutes if you trim excess fat.

Expert Tips

Don’t forget the oil

Make sure to spray the chicken with some oil, like olive oil, before air frying to help the breading get nice and crispy. Extra-virgin olive oil is the healthiest, but you can also use other oils.

Save some flour

When mixing the biscuit dough, don’t forget to save a portion of the flour to help you roll, shape, and fold. Because we replace flour with protein, it’s more sticky than traditional dough, but the extra flour makes it easy to work with. Be careful not to overwork the gluten which can result in the biscuits being tough.

Use parchment paper sheets

Parchment paper is very helpful when working on your dough because you can lift it and peel it off if it’s starting to stick. This is much easier than trying to peel the stuck dough off your counter. It’ll also keep the mess to a minimum.

Sift properly

Be sure to sift your dry ingredients together and then whisk to mix uniformly. Sifting breaks up the clumps in your ingredients and results in an even mixture.

Break down cornflakes

You can use a food processor or roll a rolling pin on a bag with the cornflakes to ensure you evenly coat the fried chicken later.

Bulk Prepping and Storage Tips

Bulk prepping and storage are great options if you’re looking to save time and enjoy this tasty and nutritious meal whenever you want. Here’s how you can do it:

Corn Flakes Breading and Biscuit

To start, you can prepare a large batch of the corn flake breading for the chicken and freeze it in an airtight container. This way, you’ll have it ready to use whenever you want to make the sandwiches.

You can also make the protein-rich biscuits ahead of time and store them in the freezer for later use. Simply wrap them tightly in plastic wrap or foil and place them in an airtight case. When ready to use, thaw them at room temperature for a few hours or overnight in the refrigerator.


You can store the cooked chicken in the refrigerator for up to three days. Let it cool completely, then place it in an airtight container or freezer bag, removing as much air as possible to prevent freezer burn.

Hot Honey Sauce

The hot honey sauce can be stored in the refrigerator for up to 3-4 months if you store it in an airtight container.

Here’s a tip: Our recipe cards allow for increased batch size. You just have to change the yield button that’s beside the “Ingredients” section. For this recipe, you can do 4, 8, or 16 yields.

Frequently Asked Questions

What condiments go with a chicken biscuit?

A classic condiment combo for a chicken biscuit includes honey, hot sauce, and mayonnaise. However, feel free to get creative and add other condiments like gravy, barbecue sauce, or even a slice of cheese. It’s all about personal preference, so go ahead and experiment until you find the perfect combination that suits your taste buds.

What is the secret to light, fluffy biscuits?

The secret to light and fluffy biscuits is to use cold ingredients and handle the dough as little as possible. Don’t overwork the dough and use a light hand when kneading or folding. Finally, remember to preheat your oven and bake the biscuits until they are golden brown on the outside and tender on the inside.

Why do you soak the chicken in buttermilk?

The acidity in buttermilk (or in this recipe’s case, vinegar) helps break down proteins, tenderize the chicken, and keep it moist during cooking. The buttermilk also infuses the chicken with more flavor.

Soaking chicken in buttermilk for several hours or overnight before cooking is a common technique used in Southern recipes, and it’s worth trying if you want to take your fried or baked chicken to the next level. Our recipe uses fat-free milk and white vinegar as a substitute for buttermilk.

What cheese goes on a chicken sandwich?

The type of cheese on a chicken sandwich varies depending on personal preference. Some popular options include cheddar, Swiss, provolone, and mozzarella.

Cheddar is a classic choice that pairs well with the bold flavors of chicken, while Swiss has a mild flavor that won’t overpower the chicken.

Provolone is a versatile option that adds a subtle nutty flavor, and mozzarella can add a creamy texture and mild taste.

Apart from cheese, other choices that go well with a chicken sandwich include bacon, avocado, lettuce, tomato, onion, pickles, and various sauces such as mayonnaise, mustard, hot sauce, or barbecue sauce.

Is a chicken biscuit healthy?

A chicken biscuit can be a part of a balanced diet, but it’s not necessarily considered a healthy food due to its high calorie, fat, and sodium content. Most chicken biscuits are made with a fried or breaded chicken patty, which can be high in calories and unhealthy fats. Additionally, the biscuit itself is usually made with white flour, butter, or shortening and may contain added sugar. 

If you’re looking for a healthier option, go for our Fried Chicken and Biscuit Sandwich recipe for reduced fat, lesser calories, and higher protein content. All without sacrificing flavor.

What do you eat with chicken biscuits?

Chicken biscuits can be enjoyed on their own as a tasty snack or as a meal, but they can also be paired with various sides and beverages to make a more filling and satisfying dish.

Some popular sides that go well with chicken biscuits include hash browns, grits, fruit, or a side salad. Beverages such as coffee, tea, juice, or milk are great options to wash down the meal. Ultimately, the best sides and beverages to pair with a chicken biscuit depend on personal preference and dietary needs.

How many calories are in a fried chicken biscuit sandwich?

The number of calories in a fried chicken biscuit sandwich can vary depending on the size and ingredients used, but on average, it can range from 500 to 700 calories. The fried chicken patty and biscuit are the main sources of calories, while any additional toppings or condiments can also contribute to the overall calorie count.

So if you’re sticking to a calorie limitation as part of your journey to being healthy, choose our recipe and enjoy Fried Chicken and Biscuit Sandwich with just over 330 calories.


Thanks for checking out our high-protein fried chicken and biscuit sandwich recipe! We’re excited to share this tasty and nutritious meal with you. By using corn flakes breading for the chicken and a protein-rich biscuit, we’ve created a sandwich that’s both delicious and filling. And our homemade hot honey sauce with fresh lettuce toppings adds a burst of flavor and nutrition that’s sure to please.

Whether you’re looking for a quick lunch or a satisfying dinner, this sandwich is a perfect choice. So go ahead and give it a try, and enjoy a tasty and healthy meal that’s sure to become a new favorite!

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